2018

Nature Scientific Reports. (IF 4.85) 2018 May 25. doi: 10.1038/s41598-018-26549-4

An in vitro method to keep human aortic tissue sections functionally and structurally intact.

Jorn P. Meekel, Menno E. Groeneveld, Natalija Bogunovic, Niels Keekstra,
René J. P. Musters, Behrouz Zandieh-Doulabi, Gerard Pals, Dimitra Micha,
Hans W. M. Niessen, Arno M. Wiersema, Jur K. Kievit, Arjan W. J. Hoksbergen,
Willem Wisselink, Jan D. Blankensteijn & Kak K. Yeung.


Translational Research. (IF 4.88) 2018 May 17. doi: 10.1016/j.trsl.2018.04.001/strong>

Prophylactic and therapeutic activity of alkaline phosphatase in arthritic rats: single-agent effects of alkaline phosphatase and synergistic effects in combination with methotrexate.

Chandrupatla DMSH, Molthoff CFM, Ritsema WIGR, Vos R, Elshof E, Matsuyama T, Low PS, Musters RJP, Hammond A, Windhorst AD, Lammertsma AA, van der Laken CJ, Brands R, Jansen G.


American Journal of Respiratory and Critical Care Medicine. (IF 13.20) 2018 Mar 26. doi: 10.1164/rccm.201709-1917OC

Positive End-expiratory Pressure Ventilation Induces Longitudinal Atrophy in Diaphragm Fibers.

Lindqvist J, van den Berg M, van der Pijl R, Hooijman PE, Beishuizen A, Elshof J, de Waard M, Girbes A, Spoelstra-de Man A, Shi ZH, van den Brom C, Bogaards S, Shen S, Strom J, Granzier H, Kole J, Musters RJP, Paul MA, Heunks LMA, Ottenheijm CAC.


Contrast media & molecular imaging. (IF 2.92) 2018 Feb 21. doi: 10.1155/2018/8092781

Imaging and Methotrexate Response Monitoring of Systemic Inflammation in Arthritic Rats Employing the Macrophage PET Tracer [18F]Fluoro-PEG-Folate.

Chandrupatla DMSH, Jansen G, Mantel E, Low PS, Matsuyama T, Musters RP,
Windhorst AD, Lammertsma AA, Molthoff CFM, van der Laken CJ.


Journal of Orthopaedic Research. (IF 2.692) 2018 Feb. doi: 10.1002/jor.23797

Mechanosensitivity of aged muscle stem cells.

Boers HE, Haroon M, Le Grand F, Bakker AD, Klein-Nulend J, Jaspers RT.


Journal of Cell Biology. (IF 7.96) 2018 Jan 22. doi: 10.1083/jcb.201606055

The Cullin-3-Rbx1-KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB.

VKovačević I, Sakaue T, Majoleé J, Pronk MC, Maekawa M, Geerts D,
Fernandez-Borja M, Higashiyama S, Hordijk PL.


Journal of Cell Biology. (IF 7.96) 2018 Jan 16. doi: 10.1083/jcb.201703206

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

Verweij FJ, Bebelman MP, Jimenez CR, Garcia-Vallejo JJ, Janssen H, Neefjes J, Knol JC, de Goeij-de Haas R, Piersma SR, Baglio SR, Verhage M, Middeldorp JM, Zomer A, van Rheenen J, Coppolino MG, Hurbain I, Raposo G, Smit MJ, Toonen RFG, van Niel G, Pegtel DM.


2017

Vascular Pharmacology. (IF 3.72) 2017 Nov 21. doi: doi: 10.1016/j.vph.2017.11.007.

The minor histocompatibility antigen 1 (HMHA1)/ArhGAP45 is a RacGAP and a novel regulator of endothelial integrity.

Amado-Azevedo J, Reinhard NR, van Bezu J, van Nieuw Amerongen GP, van
Hinsbergh VWM, Hordijk PL.


Small GTPases. (IF 3.16) 2017 Sept 26. doi: 10.1080/21541248.2017.1339767.

RhoA, RhoB and RhoC differentially regulate endothelial barrier function.

Pronk MCA, van Bezu JSM, van Nieuw Amerongen GP, van Hinsbergh VWM, Hordijk PL.


Scientific Reports. (IF 4.26) 2017 Aug 31. doi: 10.1038/s41598-017-10392-0.

A CDC42-centered signaling unit is a dominant positive regulator of endothelial integrity.

Amado-Azevedo J, Reinhard NR, van Bezu J, de Menezes RX, van Beusechem VW, van Nieuw Amerongen GP, van Hinsbergh VWM, Hordijk PL.


PLOS One. (IF 2.81) 2017 Jul 26. doi: 10.1371/journal.pone.0180912.

Tomosyn associates with secretory vesicles in neurons through its N- and C-terminal domains.

Geerts CJ, Mancini R, Chen N, Koopmans FTW, Li KW, Smit AB, van Weering JRT, Verhage M, Groffen AJA.


Angiogenesis. (IF 5.25) 2017 Jul 11. doi: 10.1007/s10456-017-9565-6. [Epub ahead of print] 

Optical clearing and fluorescence deep-tissue imaging for 3D quantitative analysis of the brain tumor microenvironment.

Lagerweij T, Dusoswa SA, Negrean A, Hendrikx EM, de Vries HE, Kole J, Garcia-Vallejo JJ, Mansvelder HD, Vandertop WP, Noske DP, Tannous BA, Musters RJ, van Kooyk Y, Wesseling P, Zhao XW, Wurdinger T.


The Journal of Physiology (London). (IF 5.04) 2017 Mar 15. doi: 10.1113/JP273589.

Rapid frequency-dependent changes in free mitochondrial calcium concentration in rat cardiac myocytes.

Wüst RC, Helmes M, Martin JL, van der Wardt TJ, Musters RJ, van der Velden J, Stienen GJ.


Circulation Heart Failure. (IF 6.83) 2017 Feb 27. doi: 10.1161/CIRCHEARTFAILURE.116.003626.

α-B Crystallin Reverses High Diastolic Stiffness of Failing Human Cardiomyocytes.

Franssen C, Kole J, Musters RJ, Hamdani N, Paulus WJ. 


Human Mutation. (IF 5.09) 2017 Jan 11. doi: 10.1002/humu.23174.

Transdifferentiation of Human Dermal Fibroblasts to Smooth Muscle-Like Cells to Study the Effect of MYH11 and ACTA2 Mutations in Aortic Aneurysms.

Yeung KK, Bogunovic N, Keekstra N, Beunders AA, Pals J, van der Kuij K, Overwater E, Wisselink W, Blankensteijn JD, van Hinsbergh VW, Musters RJ, Pals G, Micha D, Zandieh-Doulabi B.


2016

Oncotarget. (IF 6.36) 2016 Nov 15. doi: 10.18632/oncotarget.11340.

Exocytosis of polyubiquitinated proteins in bortezomib-resistant leukemia cells: a role for MARCKS in acquired resistance to proteasome inhibitors.

Franke NE, Kaspers GL, Assaraf YG, van Meerloo J, Niewerth D, Kessler FL, Poddighe PJ, Kole J, Smeets SJ, Ylstra B, Bi C, Chng WJ, Horton TM, Menezes RX, Musters RJ, Zweegman S, Jansen G, Cloos J.


Nature Communications. (IF 11.47) 2016 Jul 15;7:12210. doi: 10.1038/ncomms12210.

The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions.

Dorland YL, Malinova TS, van Stalborch AM, Grieve AG, van Geemen D, Jansen NS, de Kreuk BJ, Nawaz K, Kole J, Geerts D, Musters RJ, de Rooij J, Hordijk PL, Huveneers S.


J Neuroscience. (IF 5.99) 2016 Jun 29. doi: 10.1523/JNEUROSCI.0007-16.2016.

Extension of Helix 12 in Munc18-1 Induces Vesicle Priming.

Munch AS, Kedar GH, van Weering JR, Vazquez-Sanchez S, He E, André T, Braun T, Söllner TH, Verhage M, Sørensen JB.


PLOS Pathogens. (IF 8.06) 2016 Jun 9;12(6):e1005696. doi: 10.1371/journal.ppat.1005696. eCollection 2016 Jun.

The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10.

Ates LS, van der Woude AD, Bestebroer J, van Stempvoort G, Musters RJ, Garcia-Vallejo JJ, Picavet DI, Weerd Rv, Maletta M, Kuijl CP, van der Wel NN, Bitter W.


Mol Cell Proteomics. (IF 6.56) 2016 Apr;15(4):1281-98. doi: 10.1074/mcp.M115.052944. Epub 2016 Jan 22.

Exosomes Secreted by Apoptosis-Resistant Acute Myeloid Leukemia (AML) Blasts Harbor Regulatory Network Proteins Potentially Involved in Antagonism of Apoptosis.

Wojtuszkiewicz A, Schuurhuis GJ, Kessler FL, Piersma SR, Knol JC, Pham TV, Jansen G, Musters RJ, van Meerloo J, Assaraf YG, Kaspers GJ, Zweegman S, Cloos J, Jimenez CR.


Oncotarget. (IF 6.36) 2016 Feb 2;7(5):5240-57. doi: 10.18632/oncotarget.6169.

Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR.

Verbrugge SE, Al M, Assaraf YG, Kammerer S, Chandrupatla DM, Honeywell R, Musters RJ, Giovannetti E, O’Toole T, Scheffer GL, Krige D, de Gruijl TD, Niessen HW, Lems WF, Kramer PA, Scheper RJ, Cloos J, Ossenkoppele GJ, Peters GJ, Jansen G.